| 2000-01 | QMJHL | Rouyn-Noranda Huskies | 40 | 9 | 15 | 24 | 78 | 0 | -- | -- | -- | -- | -- | -- |
| 2000-01 | QMJHL | Hull | 24 | 6 | 7 | 13 | 60 | 0 | 5 | 1 | 0 | 1 | 2 | 0 |
| 2001-02 | QMJHL | Hull | 65 | 24 | 36 | 60 | 174 | 0 | 12 | 4 | 6 | 10 | 51 | 0 |
| 2002-03 | QMJHL | Hull | 69 | 46 | 58 | 104 | 130 | 40 | 20 | 14 | 30 | 44 | 33 | 0 |
| 2003-04 | QMJHL | Gatineau Olympiques | 51 | 25 | 73 | 98 | 41 | 33 | 15 | 11 | 16 | 27 | 0 | 0 |
| 2004-05 | AHL | Wilkes-Barre/Scranton Penguins | 75 | 7 | 12 | 19 | 62 | 7 | 11 | 0 | 1 | 1 | 22 | -2 |
| 2005-06 | AHL | Wilkes-Barre/Scranton Penguins | 42 | 12 | 20 | 32 | 80 | 12 | 11 | 3 | 6 | 9 | 16 | 8 |
| 2005-06 | NHL | Pittsburgh Penguins | 48 | 5 | 3 | 8 | 59 | -12 | -- | -- | -- | -- | -- | -- |
| 2006-07 | AHL | Wilkes-Barre/Scranton Penguins | 5 | 4 | 0 | 4 | 2 | 2 | -- | -- | -- | -- | -- | -- |
| 2006-07 | NHL | Pittsburgh Penguins | 75 | 13 | 11 | 24 | 53 | -2 | 5 | 0 | 1 | 1 | 7 | -2 |
| 2007-08 | NHL | Pittsburgh Penguins | 63 | 12 | 14 | 26 | 53 | 8 | 17 | 3 | 6 | 9 | 36 | 4 |
| 2008-09 | NHL | Pittsburgh Penguins | 75 | 12 | 10 | 22 | 63 | -9 | 24 | 8 | 5 | 13 | 19 | 8 |
| 2009-10 | NHL | Pittsburgh Penguins | 45 | 2 | 5 | 7 | 30 | -9 | 13 | 2 | 4 | 6 | 11 | 1 |
| 2010-11 | NHL | Pittsburgh Penguins | 82 | 8 | 13 | 21 | 66 | -3 | 7 | 1 | 3 | 4 | 14 | 1 |
| 2011-12 | NHL | Philadelphia Flyers | 81 | 19 | 15 | 34 | 59 | 5 | 11 | 4 | 2 | 6 | 10 | 5 |
| 2012-13 | NHL | Philadelphia Flyers | 35 | 5 | 5 | 10 | 23 | 2 | -- | -- | -- | -- | -- | -- |
| 2013-14 | NHL | Philadelphia Flyers | 11 | 1 | 1 | 2 | 2 | 1 | -- | -- | -- | -- | -- | -- |
| 2013-14 | NHL | Colorado Avalanche | 70 | 7 | 18 | 25 | 43 | 4 | 7 | 0 | 0 | 0 | 4 | -3 |
| 2014-15 | NHL | Colorado Avalanche | 63 | 5 | 10 | 15 | 27 | 2 | -- | -- | -- | -- | -- | -- |
| 2014-15 | NHL | Boston Bruins | 18 | 0 | 3 | 3 | 2 | -3 | -- | -- | -- | -- | -- | -- |
| 2015-16 | AHL | Providence Bruins | 26 | 10 | 11 | 21 | 14 | 6 | 3 | 0 | 1 | 1 | 2 | -3 |
| 2015-16 | NHL | Boston Bruins | 38 | 2 | 5 | 7 | 15 | -11 | -- | -- | -- | -- | -- | -- |
| 2016-17 | KHL | Lokomotiv Yaroslavl | 60 | 15 | 21 | 36 | 63 | 16 | 15 | 5 | 2 | 7 | 17 | -2 |
| 2017-18 | KHL | Lokomotiv Yaroslavl | 43 | 8 | 11 | 19 | 65 | 4 | 9 | 0 | 1 | 1 | 12 | -3 |
| 2018-19 | KHL | Avangard Omsk | 42 | 4 | 6 | 10 | 14 | 0 | 5 | 1 | 1 | 2 | 2 | 0 |
| NHL TOTALS | 704 | 91 | 113 | 204 | 495 | -27 | 84 | 18 | 21 | 39 | 101 | 14 |