| 91 | Tyler Seguin | C | 81 | 29 | 38 | 67 | 30 | 34 | 7 | 2 | 1 | 3 | 0 | 3 | Brampton, Ontario, CAN | 19 |
| 37 | Patrice Bergeron | C | 81 | 22 | 42 | 64 | 20 | 36 | 7 | 0 | 2 | 2 | 8 | 0 | L'Ancienne-Lorette, Quebec, CAN | 26 |
| 46 | David Krejci | C | 79 | 23 | 39 | 62 | 36 | -5 | 7 | 1 | 2 | 3 | 4 | 0 | Sternberk, CZE | 25 |
| 17 | Milan Lucic | LW | 81 | 26 | 35 | 61 | 135 | 7 | 7 | 0 | 3 | 3 | 8 | 2 | Vancouver, British Columbia, CAN | 23 |
| 63 | Brad Marchand | LW | 76 | 28 | 27 | 55 | 87 | 31 | 7 | 1 | 1 | 2 | 2 | -1 | Halifax, Nova Scotia, CAN | 23 |
| 33 | Zdeno Chara | D | 79 | 12 | 40 | 52 | 86 | 33 | 7 | 1 | 2 | 3 | 8 | -1 | Trencin, SVK | 34 |
| 17 | Rich Peverley | C | 57 | 11 | 31 | 42 | 22 | 20 | 7 | 3 | 2 | 5 | 4 | 0 | Kingston, Ontario, CAN | 29 |
| 22 | Chris Kelly | C | 82 | 20 | 19 | 39 | 41 | 33 | 7 | 1 | 2 | 3 | 4 | 1 | Toronto, Ontario, CAN | 30 |
| 8 | Nathan Horton | RW | 46 | 17 | 15 | 32 | 54 | 0 | -- | -- | -- | -- | -- | -- | Welland, Ontario, CAN | 26 |
| 67 | Benoit Pouliot | LW | 74 | 16 | 16 | 32 | 38 | 18 | 7 | 1 | 1 | 2 | 6 | -1 | Alfred, Ontario, CAN | 25 |
| 77 | Joe Corvo | D | 75 | 4 | 21 | 25 | 13 | 10 | 5 | 0 | 0 | 0 | 0 | 3 | Oak Park, Illinois, USA | 34 |
| 21 | Andrew Ference | D | 72 | 6 | 18 | 24 | 46 | 9 | 7 | 1 | 3 | 4 | 0 | -2 | Edmonton, Alberta, CAN | 32 |
| 44 | Dennis Seidenberg | D | 80 | 5 | 18 | 23 | 39 | 15 | 7 | 1 | 2 | 3 | 2 | 1 | Schwenningen, DEU | 30 |
| 9 | Gregory Campbell | C | 78 | 8 | 8 | 16 | 80 | -3 | 7 | 0 | 2 | 2 | 0 | -1 | London, Ontario, CAN | 27 |
| 12 | Brian Rolston | RW | 21 | 3 | 12 | 15 | 8 | 7 | 7 | 1 | 2 | 3 | 0 | -2 | Flint, Michigan, USA | 38 |
| 55 | Johnny Boychuk | D | 77 | 5 | 10 | 15 | 53 | 27 | 7 | 1 | 2 | 3 | 4 | 1 | Edmonton, Alberta, CAN | 27 |
| -- | Daniel Paille | LW | 69 | 9 | 6 | 15 | 15 | -5 | 7 | 1 | 0 | 1 | 2 | -1 | Welland, Ontario, CAN | 27 |
| 33 | Jordan Caron | RW | 48 | 7 | 8 | 15 | 14 | 0 | 2 | 0 | 0 | 0 | 0 | -1 | Sayabec, Quebec, CAN | 20 |
| 22 | Shawn Thornton | LW | 81 | 5 | 8 | 13 | 154 | -7 | 5 | 0 | 0 | 0 | 0 | 0 | Oshawa, Ontario, CAN | 34 |
| 54 | Adam McQuaid | D | 72 | 2 | 8 | 10 | 99 | 16 | -- | -- | -- | -- | -- | -- | Charlottetown, Prince Edward Island, CAN | 24 |
| 4 | Greg Zanon | D | 17 | 1 | 1 | 2 | 4 | 4 | 7 | 0 | 1 | 1 | 0 | 0 | Burnaby, British Columbia, CAN | 31 |
| 44 | Steven Kampfer | D | 10 | 0 | 2 | 2 | 4 | 6 | -- | -- | -- | -- | -- | -- | Ann Arbor, Michigan, USA | 23 |
| 52 | Zach Hamill | C | 16 | 0 | 2 | 2 | 4 | 3 | -- | -- | -- | -- | -- | -- | Vancouver, British Columbia, CAN | 23 |
| -- | Carter Camper | C | 3 | 1 | 0 | 1 | 0 | 1 | -- | -- | -- | -- | -- | -- | Cleveland, Ohio, USA | 23 |
| 47 | Torey Krug | D | 2 | 0 | 1 | 1 | 0 | 0 | -- | -- | -- | -- | -- | -- | Livonia, Michigan, USA | 20 |
| 42 | Trent Whitfield | C | 1 | 0 | 0 | 0 | 0 | 0 | -- | -- | -- | -- | -- | -- | Alameda, Saskatchewan, CAN | 34 |
| 22 | Mike Mottau | D | 6 | 0 | 0 | 0 | 0 | -1 | 2 | 0 | 0 | 0 | 0 | -2 | Quincy, Massachusetts, USA | 33 |
| 62 | Josh Hennessy | C | 3 | 0 | 0 | 0 | 2 | 1 | -- | -- | -- | -- | -- | -- | Brockton, Massachusetts, USA | 26 |
| 74 | Max Sauve | C | 1 | 0 | 0 | 0 | 0 | 0 | -- | -- | -- | -- | -- | -- | Tours, FRA | 21 |
| 44 | Matt Bartkowski | D | 3 | 0 | 0 | 0 | 0 | -2 | -- | -- | -- | -- | -- | -- | Pittsburgh, Pennsylvania, USA | 23 |
| 28 | Lane MacDermid | LW | 5 | 0 | 0 | 0 | 5 | -2 | -- | -- | -- | -- | -- | -- | Hartford, Connecticut, USA | 22 |
